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Additionally, we observed a decrease in M + 2-labeled malate, suggesting that M + 2-labeled citrate is properly metabolized by aconitase in the traditional TCA cycle, generating M + 2-labeled malate

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The method of any one of embodiments 79-101, wherein the composition comprises a gel or a viscous preparation

LeClerc, S

78,80,81,82 Approximately 10% of them are copy number variations (CNVs) that disrupt protein coding, including chromosomal duplications, large deletions, inversions, and translocations, such as 1q21.1 duplications or deletions, 3q29 deletions, 7q11.23 duplications, 15q11-q13 deletions, 15q13.3 microdeletions, 15q11-13 duplications, 17q12 deletions, 22q11.2 deletions and 22q13.33 duplications or deletions