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The DM-associated metabolic-immune axis further manifests in alveolar pathophysiology: obesity and T2DM induce alterations in surfactant synthesis within alveolar type II epithelial cells (Schipke et al., 2021)

When to talk to your provider Contact your provider if you experience no appetite suppression after 4 weeks of consistent use, if side effects worsen rather than improve over time, if you develop mouth sores or persistent oral irritation, or if your results plateau significantly after previously good progress

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