The SURMOUNT-1 phase 3 double-blind, randomized, controlled trial in adults with obesity without diabetes received once weekly tirzepatide (5, 10, or 15 mg) versus placebo for 72 weeks [9]
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Bloodwork Monitoring Due to its IGF-1raising effect, its advised to monitor IGF-1 levels during extended use, especially when stacking with other peptides or growth hormone boosters such as CJC-1295 or MK-677
This was a proof-of-principle that senescent cell clearance could restore organismal homeostasis
The consensus among diabetes specialists and GPs is that Mounjaro should be used as part of a comprehensive diabetes management strategy that prioritises lifestyle modificationsincluding a balanced diet, regular physical activity, and weight managementalongside pharmacological treatment