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As the lysate passes through the column, the GST tag on the fusion protein binds specifically and reversibly to the immobilized glutathione

68 However, in a population using GLP-1 RAs for obesity management without history of diabetes, increased risk of pancreatitis associated with the GLP-1 RAs was found compared to bupropion-naltrexone (HR 9.1, 95%CI 1.2566.0) suggesting the risk benefit ratio of these medications is influenced by underlying disease state

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Astrobiology 3, 785811