Environmental and emotional triggers: Sunburn, physical trauma to the skin, prolonged stress, and exposure to certain chemicals can all trigger or accelerate the spread of vitiligo in susceptible individuals
The peptide binds GHRH receptors on anterior pituitary somatotroph cells, activates adenylyl cyclase to increase intracellular cAMP, enhances transcription of the GH gene, and stimulates exocytosis of stored GH from secretory granules
Increasing both levels of ROS and reactive nitrogen species (RNS) through the destruction of cellular structures, such as DNA, proteins, and lipids, can increase the risk of migraine
They're subtle lapses that compound over weeks and silently undermine treatment outcomes before anyone realizes what happened
Dutasteride (Avodart, Duodart) for BPH: typically a 6-month deferral