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Concurrent use with insulin or sulphonylureas substantially increases hypoglycaemia risk and may require dose reductions of these medications

doi: 10.2337/dc09-S062 34 CuiXWangYTangYLiuYZhaoLDengJet al

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[1] [2] Insomnia is not listed as an adverse reaction in the Medicines and Healthcare products Regulatory Agency (MHRA) or Electronic Medicines Compendium (EMC) Summary of Product Characteristics (SmPC) for Ozempic

Cardiovascular benefits: Clinical trials have demonstrated that tirzepatide can reduce the risk of major adverse cardiovascular events, such as heart attacks and strokes, in people with type 2 diabetes who have established cardiovascular disease