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Exendin-4 and liraglutide increased the number of osteoclast precursors in mice, while the addition of mature osteoclasts reduced the absorption area, suggesting that GLP-1RA promoted osteoclast differentiation but inhibited its absorptive activity

Meaningful reduction in heart attack and stroke risk in patients with existing heart disease

We found that the relationships between impulsivity, alcohol use, and violent behavior were substantially weaker among current GLP-1 users than former users, but the study cannot establish causality, he said.

Wegovy has also been approved to reduce the risk of heart attack and stroke in people who are overweight or obese

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