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Studies in murine models indicate that IGF-1 LR3 may be cleared from the plasma faster, to be destributed more quickly into various tissue models as compared to IGF-1

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By influencing S-adenosylmethionine (SAM) levels, it also plays a role in epigenetic regulation and longevity-related gene expression, linking energy metabolism with cellular lifespan

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Moreover, liposomal formulations have been integrated with ultraviolet (UV) light therapy, demonstrating significant depigmentation effects in clinical studies [208]