In Canada and most of the European Union, its not approved for medical or cosmetic use and is considered an unregulated compound (Health Canada advisory listing AOD9604 as unauthorized)
For gastric banding patients, annual blood tests are generally recommended as a minimum once stable, covering: Serum vitamin B12 Full blood count (to detect macrocytic or megaloblastic anaemia) Serum ferritin and iron studies Vitamin D, calcium, and parathyroid hormone (PTH) Folate Thyroid function and other metabolic markers as clinically indicated The specific tests and frequency recommended may vary according to the procedure performed, individual clinical circumstances, and local protocols
Two structural modifications (C18 fatty acid chain enabling albumin binding, and a substitution at position 8 conferring DPP-4 resistance) extend its half-life to approximately 1 week, enabling once-weekly subcutaneous dosing
It is, however, crucial to maintain a stable weight in order to achieve long-lasting results
Vegans & Vegetarians Since plant-based diets often lack sufficient B12, monthly injections can prevent deficiencies