Effects of inorganic arsenic on human prostate stem-progenitor cell transformation, autophagic flux blockade, and NRF2 pathway activation
When the GLP-1 craze hit mainstream culture, they didnt just add a new service
These findings demonstrate that the therapeutic advantages of NAC go beyond temporary modulation of GSH, targeting PD pathology, including protein aggregation and neuroinflammation
12 DeLorenzoR
However, despite previous reports on the potential advantage posed by GLP1-based multi-agonists in the management of obesity and metabolic disease, as recently exemplified by the dramatic body weight-lowering actions of the GLP1/GIP dual agonist, tirzepatide 47 , to our knowledge, no study has addressed to date the pharmacological characterization of GLP1-based unimolecular multi-agonists for management of reproductive and metabolic alterations of PCOS, using suitable preclinical models, as pre-requisite for their application in clinics