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They are an adjunct to be used in combination with intensive health behavior and lifestyle treatment," Staino, who was on the AAP's clinical practice guideline authorship committee, told STAT.

While the studies supporting these benefits were not initially focused on kidney health and included patients with low kidney risk, they suggest a link between GLP-1 RAs treatment and kidney protection, especially for type 2 diabetes patients with CKD 18

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In 2007, that warning expanded to say that depression itself is linked to a higher risk of suicide