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in HT-1080 cancer cells where treatment with erastin did not cause mitochondrial ROS production 24

251,252 Elevated proteasomal activity is frequently observed in colorectal cancer (CRC), where deregulation of specific 20S proteasome subunits has been linked to carcinogenesis

Light , particularly ultraviolet (UV) radiation, can cause photodegradation a process in which light energy breaks chemical bonds within the peptide chain