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10.3390/nu14102102 [DOI] [PMC free article] [PubMed] [Google Scholar] 159.Zhang B, Xu Y, Zhao C, Zhang Y, Lv H, Ji X, Wang J, Pang W, Wang X, Wang S

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Insulin glargine was given to female rats before mating, during mating, and throughout pregnancy at doses up to 0.36 mg/kg/day, which is approximately 50 times the recommended human subcutaneous starting dosage of 0.2 units/kg/day (0.007 mg/kg/day), on a mg/kg basis

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Contact a healthcare provider if You notice signs of dehydration You have severe abdominal or rectal pain You have a fever You see blood or pus in stool You have black, tarry stool Diarrhea lasts more than 2 days in adults MedlinePlus explains that diarrhea can become dangerous if dehydration sets in or if it lasts longer than expected, and MedlinePlus lists the main diarrhea warning signs here