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Non-alcoholic fatty liver disease: Pathogenesis and clinical features NAFLD is the most common liver disease, characterized by an excessive hepatic fat accumulation in the absence of alcoholic abuse, steatogenic medications or others concomitant liver diseases (2)

Microglia, the brain resident immune cells, play an important role in the regulation of neuroinflammation and synaptic degeneration

Aberrant GTPase activity has also been implicated in various pathological conditions [176]