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It is a synthetic version of the naturally-occurring growth hormone-releasing hormone, and has been found to be safe and effective in clinical trials

Patient-derived xenografts (PDXs) and genetically engineered mouse models (GEMMs) offer more physiological insights but are limited by cost, long development times, and species-specific differences [40,41,42]

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Any GSSG initially present in the reaction mixture or formed from the mixed disulfide reaction of GSH with GS-TNB is rapidly reduced to GSH and detectable in the assay

Aubrey, B