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Antibodies directed against tau protein, including semorinemab, tilavonemab, and gosuranemab, have shown unpromising preliminary results and fail to improve global patient functionality (Monteiro et al., 2023)

Its proposed mechanisms are complex and multifaceted, involving interactions with the nitric oxide (NO) system, influence on growth factor expression (like Vascular Endothelial Growth Factor or VEGF), and modulation of cellular pathways related to tissue repair

(115) reported that purified blueberry polyphenol extract exhibited higher antioxidant activity in different in vitro assays, whereas the crude blueberry extract demonstrated greater antioxidant effectiveness in in vivo models

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Endreffy I, Bjrklund G, Dics F, Urbina MA, Endreffy E (2016) Acid glycosaminoglycan (aGAG) excretion is increased in children with autism spectrum disorder, and it can be controlled by diet