With the advent of GLP-1 mimetics like liraglutide and semaglutide, obese individuals now have access to approved alternatives for weight management beyond traditional methods, marking a significant shift in obesity treatment without the prerequisite of diabetes [1]
The published mechanistic literature has converged on the HGF/c-Met receptor system as the primary molecular target, with downstream effects on dendritic synaptogenesis and PI3K/AKT signaling
Itraconazole and ketoconazole exhibit weak in vitro efficacy against Fusarium and Aspergillus species [60]
Additional factors, such as cohort differences, dietary habits, and timing of food intake, may also contribute, as the studies are based on spot urine samples
Personalized Plans: Each patient receives a tailored care plan, integrating medication with nutrition guidance, exercise recommendations, and behavioral support