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Psychiatric genetics 16, 105115, doi:10.1097/01.ypg.0000199444.77291.e2 (2006)

13 Investigations in humans have used 15 mg/kg as an oral bolus to increase the plasma GSH concentration two- to fivefold

People with uncontrolled heart, kidney, or thyroid conditions, those who are pregnant or breastfeeding, and anyone with a history of severe allergic reactions to injectable medications

The mechanisms underlying these effects include the inhibition of protein tyrosine phosphatase 1B (PTP1B), which is physiologically responsible for insulin receptor inhibition through dephosphorylation and attenuates insulin signal transduction (123, 124)

Regular blood tests are important to monitor thyroid levels and adjust the dosage if necessary