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Some people with alcohol use disorder experience weight gain, insulin resistance, and metabolic-associated steatotic liver disease (MASLD)

The median BMI at initiation of a GLP-1 RA was ~34, more than three-quarters had a diabetes diagnosis, and many were on concurrent endocrine therapy

NICE recommends Saxenda only within specialist weight management services (Tier 3 or 4) for adults meeting specific BMI and comorbidity criteria

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The longer answer which is what the rest of this guide is about explains why, what's actually in the patches, what the science says about transdermal weight loss, and what works instead if you're serious about losing weight