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Frequently Asked Questions Will I feel exhausted every time I start or increase my tirzepatide dose

You may experience a gap between how you see yourself and how your body looks, grief or confusion around identity, or even disappointment if the changes don't meet your expectations

Cleveland Clinic and Mayo Clinic both note that these medicines should be started carefully and usually need dose escalation under medical supervision

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When the drug is removed, a big risk is weight regain without re-building muscle, worsening insulin resistance and leaving the patient with a condition called sarcopenic obesity potentially worse off than prior to taking the GLP-1