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To date, the findings suggest an increasing prevalence of T2DM in both urban and rural areas, but with a comparatively steeper rise in the urban setting that is driven by rapid changes in dietary practices and greater physical inactivity compared to rural areas

Additionally, the precise dosages of SFN that subjects received from these formulations are difficult to quantify, and the efficacy of SFN in clinical trials may be influenced ( Thirdly, the selection of dose and dose schedule of SFN needs to be optimized in future studies

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