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Symptoms of a serious allergic reaction may include skin rash, raised red patches on your skin (hives), swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing

References Hornsby, C., Bains, J

Other substituents engage in interactions with the amino acid residues of Phe357, Ser209, and Arg358 within the S2 pocket as shown in (Figure 2)

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