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When GLP-1 therapy is combined with lifestyle changes improvements in cholesterol, blood pressure, and other cardiometabolic markers become even more pronounced and may help explain why cardiovascular benefits observed during therapy often appear larger than what weight loss alone would predict

Sometimes its not the weight loss thats going to improve their outcomes, but the weight loss thats needed to be able to access these more advanced and successful treatments [because of BMI limits in some IVF programs], Boots said

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Treatment adherence is improving: persistence improved from ~40% for those starting treatment in 2023 to 63% for those beginning in early 2024 (one-year continuation)

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