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Some researchers follow 2-months-on, 1-month-off cycling patterns to prevent potential receptor downregulation

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Neurogenesis, synaptic plasticity, and metabolic support GLP-1R stimulation promotes hippocampal neurogenesis and enhances synaptic plasticity, partly through brain-derived neurotrophic factor and modulation of glutamatergic signalling

Research has shown that GLP-1 receptor agonists can reduce visceral adipose tissue by as much as 18% in individuals with PCOS

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