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Many ASD children present new types of mitochondria dysfunction, e.g., metabolic disturbances (inborn errors of amino acids metabolism in maple syrup disease (MSUD), dysregulation of the immunological system (ASD development may be connected with an increase in proinflammatory cytokines in natal-and perinatal periods) and/or inflammation in the nervous system, and oxidative stress (increased production of the reactive oxygen species)

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Since these compounds are water-soluble, the body may safely process them without risk of accumulation [11]

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