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While somatostatin secreted from -cells inhibited glucagon secretion, a somatostatin antagonist only partially blunted the GLP-1-induced decrease in glucagon (89) suggesting additional mechanisms at play

Figure 1 The operation of glutamineglutamate (GABA) cycle in one direction only is a result of the astrocyte -specific (probably not glia- specific) localizations of the enzymes pyruvate carboxylase, PC (Yu et al., 1983

van Malderen et al., 2025

NextGenPeps provides PT-141 exclusively for laboratory research use in vitro or in ethically approved animal studies

This peptide is designated for research purposes only and is not intended for therapeutic, cosmetic, or diagnostic applications