glp-1 mimetics actions and target organs. GLP-1, through its receptor GLP-1R, Possible mechanisms of action of

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[Abstract] The expression of NHE7 in Dox-inducible NHE7-mAID-KO MHCC97L cells with or without doxycycline (DOX, 2 mg/mL) and indole-3-acetic acid (IAA, 50 g/mL) treatment for 24 h was examined by immunoblotting

Our patch-clamp electrophysiology results corroborate these findings, demonstrating that GLP-1RAs directly activate DMH GLP-1R neurons, which in turn send inhibitory projections to ARC AgRP/NPY neurons [69]

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