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Future research should prioritize elucidating the molecular mechanisms behind the antitumor effects, refining individualized treatment strategies, investigating early tumor prevention applications, assessing potential benefits for non-diabetic populations, advancing the development of novel therapies, establishing robust safety monitoring frameworks, and building precision medicine decision-making platforms

, tumor protein p53 (TP53, also known as p53) and nuclear factor-B (NF-B), and activator protein 1 (AP-1)), kinases ( e.g