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Catecholamine Catabolism The catecholamine, DOPA, dopamine, epinephrine, and norepinephrine are catabolized to inactive compounds through the sequential actions of enzymes that include catecholamine- O -methyltransferase (COMT) and monoamine oxidase (MAO)

However, it was discontinued as monotherapy for MASH after phase III trials failed to demonstrate sustained antifibrotic efficacy (179)

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This issue was further examined by evaluating the impact of HGF treated by GSSSG or LASSS on activation of myogenic stem satellite cells in culture (Figure 1d)

Kaur, K., Carrazzone, R