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Research suggests semaglutide may be associated with a four times higher risk of developing a rare form of blindness called nonarteritic anterior ischemic optic neuropathy when used to treat Type 2 diabetes, and a seven times higher risk when used for obesity

The foods that tend to be best tolerated in this window are: Lower-fat preparations (grilled rather than fried, baked rather than sauted) Smaller volumes more frequently Bland-to-moderate seasoning (spicy food is a very common trigger) Room-temperature or cool foods (hot, aromatic meals can provoke nausea) This is temporary

doi:10.1152/ajprenal.00536.2012 60

This cascade of effects has wide-ranging implications for anyone trying to improve their body composition

Semaglutide versus tirzepatide represents the most common comparison