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Such an outcome would be a disaster for Novo Nordisk

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Naltrexone may be prescribed alone when a single behavioral driver is identified or combined with bupropion when multiple neurobehavioral factors affect treatment response

Under this model, kidney function achieved significance as mediating ~20% of the positive association between age and circulating TMAO levels in BMIS with its impact further strengthening in the T2D (55%) and IHD (51%) disease groups (Supplementary Fig