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Vasoplegic syndrome is a state of profoundly low systemic vascular resistance secondary to aberrant nitric oxide production, release, and signaling

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This is important given the rich innervation of the airway and its modulatory role in mucus secretion [14,15,16,17,18,19]

The committees recommendation is advisory, and the FDA will now review the recommendation, public comments and the administrative record before determining whether to move forward with rulemaking