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[DOI] [PubMed] [Google Scholar] 49.Ishii S., Nagai Y., Sada Y., Fukuda H., Nakamura Y., Matsuba R., Nakagawa T., Kato H., Tanaka Y

In a pre-specified extension cohort restricted to participants with a BMI of at least 35, average weight loss reached 30.3% at 104 weeks

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A pivotal 1984 Massachusetts study led to the groundbreaking discovery of GLP-1, revealing that it stimulated insulin secretion from the pancreas in response to food intake