Other recognised adverse effects include: Injection site reactions (redness, itching) Fatigue (uncommon) Dizziness (uncommon) A modest increase in heart rate has been observed Gallbladder disorders , including cholecystitis and cholelithiasis Diabetic retinopathy complications (particularly in patients with pre-existing retinopathy and rapid improvement in glycaemic control) Acute pancreatitis (uncommon) Dysgeusia (taste disturbance) Increases in pancreatic enzymes (amylase/lipase) Serious allergic reactions, though rare, require immediate medical attention
Different forms of semaglutide are approved for use in people with diabetes, or for weight loss in people who are significantly overweight
34 A prospective, singlearm, multicentre study in Japan, evaluating 58 patients who switched from exenatide twice daily to exenatide ER, observed improved glycaemic control (HbA 1c decrease of 0.2%point over 24 weeks)
If you have IBS-C, go in with eyes open: you may need to adjust your diet or medications to prevent a back-up
They consistently showed higher risk of mild to moderate gastrointestinal side effects in patients treated with GLP-1 receptor agonists
