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The largest pulses occur during deep sleep

Parvanova, M.T., C.A., I.I., R.T., and A.C.B

Initial titration over 714 days allows researchers to identify dose-limiting side effects before committing to higher therapeutic doses

The gastrointestinal side effects for both sexes peaked during weeks 6-8 (the dose escalation period) and resolved substantially by week 12 once the body adapted to the maintenance dose

While as little as 1 gram of L-carnitine can be effective, your best bet is to take 2-3 grams per dose for maximum benefit, along with at least 30-40 grams of carbs and 20-40 grams of protein, preferably with a meal