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At the same time, endocrinologists and health care providers are also increasingly prescribing them as these medications help in diabetes control, treating heart failure, reducing the progression of kidney disease, managing and reversing fatty liver, and multiple other metabolic and mechanical problems, Dr Asim Maldar, consultant endocrinologist and diabetes specialist, PD Hinduja Hospital and Medical Research Centre, Mumbai, tells Forbes India

If you don't see results after 4 to 8 weeks, it could be due to low bioavailability (using standard pills instead of liposomal forms) or a high "toxic load" that is depleting your levels as fast as you can replenish them

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Orlistat-treated patients ended up having lost 12.8 pounds (5.8 kg), compared to 6.6 pounds (3.0 kg) in those receiving a placebo

2026;doi:10.1001/jamaophthalmol.2025.6262