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The pleotropic roles of NAD + enable several possible avenues by which repletion of this coenzyme could have therapeutic efficacy

Interestingly, after a week-long suppression of the gut microbiota with oral broad-spectrum antibiotics cocktail, a rechallenge with oral d 9 -BB showed complete suppression of d 9 -TMAO formation in subjects, confirming gut microbiotadependent conversion of BB into TMAO (Figure 2A, open circles)

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[DOI] [PubMed] [Google Scholar] 54.Bronowicka-Adamska P., Zagajewski J., Czubak J., Wrbel M

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