The physiological adaptations over time need to be considered
However, development was discontinued in 2007 after the largest Phase IIb trial failed to demonstrate statistically significant weight loss compared to placebo
Vitamin B12 is essential for growth, blood formation, cell reproduction, and tissue synthesis
Vitamin B12 deficiency can be caused by several factors, including: Inadequate dietary intake: Since vitamin B12 is naturally found in animal-based foods, strict vegetarians and vegans who do not consume fortified foods or supplements are at risk of developing a deficiency
In animal models of metabolic disease, JBSNF-000088 treatment reduced MNA levels and drove insulin sensitization, glucose modulation, and body weight reduction