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Studies have shown that changes in gut microbiota composition can influence the brain via the vagus nerve, production of neurotransmitters such as serotonin, and systemic inflammation, contributing to both gastrointestinal symptoms and psychological comorbidities like anxiety and depression ( 5 Gut microbiota and gastrointestinal diseases The gut microbiota has been increasingly linked to the development and progression of various cancers, including colorectal cancer

Cancer Cell 3 , 285296 (2003)