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Similarly, RDP58, a peptide-based anti-inflammatory agent, improved colitis in mice by enhancing microbial diversity and promoting short-chain fatty acid (SCFA)-producing bacteria, which in turn stimulated regulatory T cell (Treg) differentiationa critical anti-inflammatory mechanism

Most researchers report initial subtle improvements within 7 to 10 days, with significant changes in sleep quality emerging over 3 to 6 weeks

doi: 10.1073/pnas.1001006107 56 OuYWangSJLiDChuBGuW

Mitoxantrone-induced suicidal erythrocyte death

4-hydroxyestrone, an endogenous estrogen metabolite, can strongly protect neuronal cells against oxidative damage