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NRF2 addiction in cancer cells

543 Furthermore, AMPK is vital for regulating lipid metabolism by curbing fatty acid synthesis and enhancing -oxidation, which impacts metabolic balance

While in Merrifield's laboratory, both as a doctoral student and then as a postdoctoral fellow, Mojsov had mastered his solid phase method for the synthesis of glucagon which many others had struggled to replicate

Inhibiting -oxidation protects ER function through glutathione redox We and others have previously shown that etomoxir raises the cellular ratio of oxidized (GSSG) to reduced (GSH) glutathione (Merrill et al., 2002