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Abstract We report the design and target validation of chimeric peptide EP45, a novel 45 amino acid monomeric dual agonist peptide that contains amino acid sequence motifs present within the blood glucose-lowering agent exendin-4 (Ex-4) and the appetite-suppressing agent PYY(336)

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Rotate injection sites every week to avoid repeating the same area, which accumulates microtrauma and increases inflammation

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