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For ICRs under OMB control number 0938-1314 (CMS-10621), we estimate that the policies finalized in this final rule will result in 2,312 additional responses due to the availability of new MIPS Value Pathways (MVPs)

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A dose-dependent superiority in lowering HbA 1c was evident with all three tirzepatide doses vs all comparators, with mean differences ranging from 17.71 mmol/mol (1.62%) to 22.35 mmol/mol (2.06%) vs placebo, 3.22 mmol/mol (0.29%) to 10.06 mmol/mol (0.92%) vs GLP-1 RAs, and 7.66 mmol/mol (0.70%) to 12.02 mmol/mol (1.09%) vs basal insulin regimens

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