Because of the risk of addiction or abuse, such stimulant drugs are "controlled substances," which means they need a special type of prescription
Various pharmacies offer compounded tirzepatide with different added ingredients, including formulations with glycine and B12
Interestingly, agmatine, a metabolite produced by the gut bacterium Bacteroides vulgatus was shown to impair ovarian function by inhibiting GLP-1 secretion through activation of the farnesoid X receptor (FXR) (Yun et al., 2024)
While the onset of fatigue may be challenging, its temporary nature offers reassurance to those considering or currently using Ozempic (semaglutide), Wegovy (semaglutide), or compounded semaglutide for their wellness goals
It comes as a tablet, not a liquid, but many people search for "GLP-1 oral liquid" when they actually mean any oral GLP-1 formulation