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Role of Food Antioxidants in Modulating Gut Microbial Communities: Novel Understandings in Intestinal Oxidative Stress Damage and Their Impact on Host Health

In glycolysis, glucose is broken down into pyruvate producing a small amount of ATP while in OXPHOS, metabolized pyruvate products feed electrons through the electron transport chain to generate a proton gradient that makes a much larger amount of ATP

Some research have reported that the imbalance of intestinal homeostasis in recent years, including activation of intestinal mucosal immunity, disturbance of intestinal microbiome and epithelial barrier damage, may be involved to the process of RA (Bennike et al., 2017

4,44 Schwann cells are also targeted by chronic hyperglycemia, leading to demyelination features in severe cases

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