[9] This is made possible by the rapid reduction of nitrofurantoin inside the bacterial cell by flavoproteins (nitrofuran reductase) to multiple reactive intermediates that attack ribosomal proteins, DNA, [60] respiration, pyruvate metabolism and other macromolecules within the cell
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LOsG did not alter expressions of pancreatic ER stress, inflammation, and hypoxia-responsive genes It has been suggested that endoplasmic reticulum (ER) stress, inflammation, and hypoxia are related to the underlying mechanism of -cell dedifferentiation 28
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