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doi: 10.2337/db18-1123 3 GasbjergLSHelstedMMHartmannBSparre-UlrichAHVeedfaldSStensenSet al

We provide ongoing guidance, monitoring your progress and making adjustments as needed

For example, current Wegovy injection labeling uses a staged escalation schedule that extends beyond 12 weeks before the standard maintenance stage

Bottom line Stopping a GLP-1 doesn't automatically mean you'll regain all the weight you've lost or lose every health benefit you've gained

Differences in inclusion criteria, patient demographics, and study design could account for these discrepancies, yet nonetheless evidence exists that GLP-1 activity likely influences mesolimbic signaling through a complex and not yet fully understood mechanism