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doi: 10.3389/fmolb.2021.649151 Received 04 January 2021 Accepted 12 February 2021 Published 13 April 2021 Volume 8 - 2021 Edited by Graa Soveral, University of Lisbon, Portugal Reviewed by Pdraig D'Arcy, Linkping University, Sweden Benita Sjogren, Purdue University, United States Updates Copyright 2021 Chen, Dou, Liu and Tang

This mechanism provides a valuable research model for investigating aging biology, cell-cycle regulation, and the role of senescent cells in tissue function