doi: 10.1038/srep26419 26 MoalliPAPillaySKrettNLRosenST
Similarly, a renal transporter is often referred to as a reabsorption transporter if it is expressed in the apical membrane, however, there are both uptake (reabsorption into the cell) and efflux (secretion into the tubular lumen) transporters in the apical membrane as in the basolateral membrane
NLY01 did not show any effects in a phase II clinical trial in patients with PD in the primary and secondary readouts (NCT04154072) [211]
However, the role of major antioxidant molecules in the human body, such as glutathione, ascorbic acid and uric acid, has been neglected in this context
Narala VR, Narala SR, Aiya Subramani P, Panati K, Kolliputi N