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Currently, there is no unified standard for senescence biomarkers [16]

Neurology 90 , e254e260 (2018)

K., Nam, S

RNA sequencing revealed extensive transcriptional reprogramming following cold acclimation, characterized by upregulation of pathways related to ribosome biogenesis, RNA processing, transcriptional regulation, and protein quality control, and downregulation of gene sets involved in DNA replication, DNA repair, and cell cycle progression, consistent with adaptive cellular remodeling